SCHEMBL29279028

SCHEMBL29279028

COC(C)OC(=O)C(C)(C)OC(=O)c1cc(N=C=O)c(F)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24152223 0.83 CYP1A2 (0.36) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL29279027 0.82 GAA (0.36) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL29171458 0.81 LMNA (0.37) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL9477488 0.79 LMNA (0.40) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL7682549 0.78 GAA (0.41) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL10913907 0.78 MAPT (0.38) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL29278997 0.77 GUSB (0.38) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL10916815 0.72 CYP4F2 (0.47) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL9423172 0.71 POLB (0.37) LMNAMAPTHPGDSMN1; SMN2POLB
SCHEMBL25283708 0.70 HPGD (0.38) LMNAMAPTHPGDSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551043-A Method for preparing uracil compound containing carboxylic ester fragment by using isocyanate as raw material 江苏中旗科技股份有限公司 2024-02-13 CN disclosed