Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471483 | 0.88 | LMNA (0.40) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL7682549 | 0.85 | GAA (0.41) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL10986658 | 0.84 | CA12 (0.36) | LMNAMAPTHPGDALDH1A1CA12 | |
| SCHEMBL9423172 | 0.83 | POLB (0.37) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL25283707 | 0.81 | HPGD (0.38) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL25283708 | 0.81 | HPGD (0.38) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10916815 | 0.81 | CYP4F2 (0.47) | LMNAMAPTHPGDSMN1; SMN2CA12 | |
| SCHEMBL9247954 | 0.81 | HPGD (0.56) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL29279028 | 0.79 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL30987203 | 0.78 | KEAP1 (0.39) | LMNAMAPTHPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221744-A | Herbicides | SANDOZ LTD. (CH) | 1993-06-22 | — | — | US | disclosed |
| EP-0514339-A1 | Novel arylaminocarbonyl compounds | SANDOZ LTD. (CH) | 1992-11-19 | — | — | EP | disclosed |
| US-5041156-A | 3-aryluracils for the control of weeds | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-4927451-A | HERBICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4812164-A | PYRIMIDINES | HOFFMANN-LA ROCHE INC. (US) | 1989-03-14 | — | — | US | disclosed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0104532-B1 | O-HALOBENZOIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS AND THEIR USE | Nippon Kayaku Kabushiki Kaisha (JP) | 1986-12-03 | — | — | EP | disclosed |
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| US-4531964-A | Heterocyclic compound and a herbicidal composition containing said compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0104532-A1 | O-Halobenzoic acid derivatives, process for their preparation, herbicidal compositions and their use | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |