Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279590 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL29279545 | 0.78 | HTR2A (0.54) | TSHRHTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL27002173 | 0.75 | HTR2A (0.45) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL27002188 | 0.74 | HTR2A (0.44) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL11093194 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL27002026 | 0.74 | AR (0.43) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL27002017 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL11584615 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL29279527 | 0.69 | HTR2A (0.54) | TSHRHTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL27002006 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TSHRFDPSHPGDTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |