Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.54 |
| ▸ | HTR2C | P28335 | 9/20 | 0.47 |
| ▸ | HTR2B | P41595 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279527 | 0.92 | HTR2A (0.54) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26061242 | 0.80 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL29279531 | 0.78 | ALDH1A1 (0.38) | HTR2AHTR2CHTR2BTSHRMAPK1 | |
| SCHEMBL26056043 | 0.77 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26056124 | 0.76 | HTR2A (0.62) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL20970855 | 0.76 | HTR2A (0.61) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002187 | 0.75 | HTR2A (0.58) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002186 | 0.75 | HTR2A (0.54) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002101 | 0.74 | HTR2A (0.57) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002071 | 0.73 | HTR2A (0.51) | HTR2AHTR2CHTR2BKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |