SCHEMBL29280618

SCHEMBL29280618

COC(=O)C(O)(c1ccccc1)c1ccc(F)cc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.44
NR3C2 P08235 1/20 0.40
NOTUM Q6P988 1/20 0.40
GAA P10253 1/20 0.39
SRC P12931 1/20 0.38
PKM P14618 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.38
PLK4 O00444 1/20 0.38
DAPK3 O43293 1/20 0.38
RPS6KA5 O75582 1/20 0.38
MAP4K4 O95819 1/20 0.38
ERBB2 P04626 1/20 0.38
PRKCG P05129 1/20 0.38
PIM1 P11309 1/20 0.38
PHKG2 P15735 1/20 0.38
CDK2 P24941 1/20 0.38
AXL P30530 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29280629 0.89 KCNN4 (0.44) KCNN4NR3C2GAASRCPKM
SCHEMBL29280645 0.85 MEN1 (0.46) KCNN4GAASRCNPC1RAB9A
SCHEMBL29280633 0.83 KCNN4 (0.51) KCNN4GAASRCNPC1RAB9A
SCHEMBL29280625 0.76 RAB9A (0.41) PKMNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL1870824 0.75 KCNN4 (0.67) KCNN4GAASRCMAPTCHRM3
SCHEMBL3178998 0.73 KCNN4 (0.43) KCNN4GAANPC1RAB9ASMN1; SMN2
SCHEMBL3173332 0.73 KCNN4 (0.50) KCNN4NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL3169534 0.72 RAB9A (0.44) KCNN4GAASRCNPC1RAB9A
SCHEMBL29280605 0.72 KMT2A (0.44) KCNN4GAANPC1RAB9ASMN1; SMN2
SCHEMBL29280630 0.72 RAB9A (0.46) KCNN4GAANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777172-A Benzo five-membered ring boric acid ester-3-carboxylic acid compound and application thereof 四川大学 2024-03-29 CN disclosed