Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280618 | 0.89 | KCNN4 (0.44) | KCNN4NR3C2GAASRCPLK4 | |
| SCHEMBL29280633 | 0.83 | KCNN4 (0.51) | KCNN4GAASRCMAPTCHRM3 | |
| SCHEMBL19926550 | 0.77 | NPSR1 (0.41) | NR3C1MAPTMEN1LMNAKMT2A | |
| SCHEMBL181881 | 0.77 | NOTUM (0.39) | NR3C1MAPTMEN1LMNAKMT2A | |
| SCHEMBL29280645 | 0.77 | MEN1 (0.46) | KCNN4GAASRCMAPTMEN1 | |
| SCHEMBL1870824 | 0.75 | KCNN4 (0.67) | KCNN4GAASRCMAPTCHRM3 | |
| SCHEMBL3173332 | 0.73 | KCNN4 (0.50) | KCNN4MAPTMEN1LMNAKMT2A | |
| SCHEMBL3172763 | 0.73 | CES2 (0.40) | GAAMAPTMEN1LMNAKMT2A | |
| SCHEMBL3169534 | 0.72 | RAB9A (0.44) | KCNN4GAASRCMAPTMEN1 | |
| SCHEMBL29280605 | 0.72 | KMT2A (0.44) | KCNN4GAAPLK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777172-A | Benzo five-membered ring boric acid ester-3-carboxylic acid compound and application thereof | 四川大学 | 2024-03-29 | — | — | CN | disclosed |