Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27806680 | 1.00 | CA1 (0.39) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL4592112 | 0.96 | — | — | |
| Bicarbonate SCHEMBL2334734 | 0.96 | CA1 (0.42) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL2122167 | 0.96 | — | — | |
| Bicarbonate SCHEMBL21598431 | 0.96 | — | — | |
| Bicarbonate SCHEMBL27963055 | 0.92 | CA1 (0.46) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL2782263 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28151662 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL3244968 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL4600958 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117825555-A | Method for detecting polyunsaturated fatty acid in blood by liquid chromatography-mass spectrometry | 大连博源医学科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117825555-A | Method for detecting polyunsaturated fatty acid in blood by liquid chromatography-mass spectrometry | 大连博源医学科技有限公司 | 2024-04-05 | — | — | CN | disclosed |