⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28665424 | 0.98 | CHRNA4 (0.41) | — | |
| Biphenyl SCHEMBL27390408 | 0.88 | TRPM8 (0.43) | — | |
| SCHEMBL23042189 | 0.79 | CHRNA4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL29099329 | 0.77 | NAMPT (0.45) | — | |
| SCHEMBL28317573 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL249355 | 0.76 | — | — | |
| SCHEMBL27892844 | 0.75 | CHRNA4 (0.44) | — | |
| SCHEMBL3139867 | 0.74 | ACACB (0.36) | — | |
| SCHEMBL28045846 | 0.73 | CA12 (0.41) | — | |
| SCHEMBL28316679 | 0.73 | CHRNA4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772346-B | Bicyclol prodrug compound, and preparation method, pharmaceutical composition and application thereof | SHANGHAI YUEXING INTELLECTUAL PROPERTY AGENCY CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-103772346-A | Bicyclol prodrug compound, and preparation method, pharmaceutical composition and application thereof | SHANGHAI YUEXING INTELLECTUAL PROPERTY AGENCY CO LTD | 2014-05-07 | — | — | CN | claimed |
| CN-115515962-B | Fused isoxazoline derivatives and their use as herbicides | 巴斯夫欧洲公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-115210222-B | Dioxazolines and their use as herbicides | 巴斯夫欧洲公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-112424194-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117279905-A | Carboxy-benzimidazole GLP-1R modulating compounds | 吉利德科学公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-112707893-B | 1-cyanopyrrolidine compounds as USP30 inhibitors | 特殊治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-111278821-B | Spiro compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116568310-A | Boric acid compounds | 株式会社LG化学 | 2023-08-08 | — | — | CN | disclosed |
| US-20090192317-A1 | PROCESS FOR THE SYNTHESIS OF 2-AMINOXAZOLE COMPOUNDS | AB SCIENCE (FR) | 2009-07-30 | — | — | US | disclosed |
| EP-2019822-A1 | A NEW PROCESS FOR THE SYNTHESIS OF 2-AMINOXAZOLE COMPOUNDS | AB Science (FR) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007131953-A1 | A NEW PROCESS FOR THE SYNTHESIS OF 2-AMINOXAZOLE COMPOUNDS | AB SCIENCE (FR) | 2007-11-22 | — | — | WO | disclosed |
| CN-1950365-A | Indolyl derivatives as liver-X-receptor modulators | HOFFMANN LA ROCHE (CH) | 2007-04-18 | — | — | CN | disclosed |
| EP-0702683-B1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2003-09-17 | — | — | EP | disclosed |
| CN-1048493-C | 06-substituted guanine derivatives, a process for their prepn. and their use | CANCER RES CAMPAIGN TECH (GB) | 2000-01-19 | — | — | CN | disclosed |
| CN-1145622-A | O 6Substituted guanine derivatives, process for their preparation and their use | CANCER RES CAMPAIGN TECH (GB) | 1997-03-19 | — | — | CN | disclosed |
| CN-1143958-A | (4,4-difluorobut-3-enylthio-)-substituted heterocyclic or carbocyclic ring compounds | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |
| EP-0696283-A1 | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- AND/OR 10-SUBSTITUTED DIBENZOXAZEPINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SEARLE & CO (US) | 1996-02-14 | — | — | EP | disclosed |