Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281020 | 0.89 | TP53 (0.32) | MDM2 | |
| SCHEMBL29281008 | 0.87 | TP53 (0.31) | MDM2 | |
| SCHEMBL29280974 | 0.87 | PTGS1 (0.31) | MDM2 | |
| SCHEMBL29280984 | 0.80 | EDNRB (0.35) | P2RX3EDNRBEDNRAMDM2 | |
| SCHEMBL30296014 | 0.73 | EDNRB (0.36) | EDNRBEDNRA | |
| SCHEMBL30295779 | 0.70 | EDNRB (0.38) | EDNRBEDNRA | |
| SCHEMBL29281019 | 0.69 | ALOX5AP (0.34) | MDM2 | |
| SCHEMBL29281006 | 0.68 | ALOX5AP (0.33) | MDM2 | |
| SCHEMBL29280972 | 0.67 | ALOX5AP (0.34) | MDM2 | |
| SCHEMBL11046847 | 0.64 | CA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |