Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296047 | 0.89 | EDNRB (0.42) | ALDH1A1TP53MAPTGAAEDNRA | |
| SCHEMBL30844549 | 0.88 | ALPL (0.33) | TSHRALDH1A1TP53MAPTGAA | |
| SCHEMBL5529373 | 0.87 | RORC (0.36) | EDNRA | |
| SCHEMBL5528962 | 0.87 | GAA (0.32) | TSHRALDH1A1MAPTGAAEDNRA | |
| SCHEMBL5521626 | 0.85 | MEN1 (0.36) | TSHRALDH1A1MAPTEDNRACYP2C9 | |
| SCHEMBL30517192 | 0.84 | EDNRA (0.38) | TSHRALDH1A1TP53MAPTEDNRA | |
| SCHEMBL30844596 | 0.84 | ALPL (0.31) | TP53 | |
| SCHEMBL6694770 | 0.84 | EDNRA (0.40) | TSHRALDH1A1TP53MAPTGAA | |
| SCHEMBL26688761 | 0.84 | EDNRA (0.40) | TSHRALDH1A1TP53MAPTGAA | |
| SCHEMBL29799735 | 0.84 | EDNRA (0.40) | TSHRALDH1A1TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |