Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 5/20 | 0.40 |
| ▸ | EDNRB | P24530 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 2/20 | 0.34 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280982 | 0.89 | CCNT1 (0.41) | EDNRAEDNRBCCNT1CDK9BRD4 | |
| SCHEMBL30296201 | 0.87 | EDNRA (0.51) | EDNRAEDNRBAGTR1 | |
| SCHEMBL29281018 | 0.84 | EDNRA (0.37) | EDNRAEDNRBCCNT1CDK9BRD4 | |
| SCHEMBL29280988 | 0.83 | EDNRA (0.36) | EDNRAEDNRBCCNT1CDK9BRD4 | |
| SCHEMBL29281011 | 0.80 | EDNRA (0.44) | EDNRAEDNRBAGTR1 | |
| SCHEMBL30296014 | 0.76 | EDNRB (0.36) | EDNRAEDNRBALDH1A1LMNA | |
| SCHEMBL30296109 | 0.75 | EDNRA (0.48) | EDNRAEDNRBCCNT1CDK9AGTR1 | |
| SCHEMBL30171018 | 0.73 | EDNRA (0.56) | EDNRAEDNRBCCNT1CDK9AGTR1 | |
| SCHEMBL30296080 | 0.72 | EDNRA (0.46) | EDNRAEDNRBCCNT1CDK9AGTR1 | |
| SCHEMBL29280981 | 0.70 | EDNRA (0.44) | EDNRAEDNRBCCNT1CDK9AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |