SCHEMBL2928119

SCHEMBL2928119

Cc1onc(C(=N)N)c1O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.32
GRIA3 P42263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4400853 0.67 ALDH1A1 (0.39)
SCHEMBL28077375 0.66
SCHEMBL2617349 0.66
SCHEMBL4781070 0.64
SCHEMBL2676823 0.62 MEN1 (0.41) GRIA1GRIA3
SCHEMBL1831780 0.61
Hydrochloric Acid SCHEMBL25417675 0.60 KDM4E (0.39)
SCHEMBL29281024 0.60 MEN1 (0.39) GRIA1GRIA3
Hydrazine SCHEMBL28457919 0.58 AKT1 (0.34)
SCHEMBL6866293 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2227466-A2 HETEROARYL-SUBSTITUTED PIPERIDINES Bayer Schering Pharma Aktiengesellschaft (DE) 2010-09-15 EP disclosed
WO-2009068214-A2 HETEROARYL-SUBSTITUTED PIPERIDINES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-06-04 WO disclosed