Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855640 | 1.00 | TGFBR1 (0.60) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30855625 | 0.90 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281220 | 0.90 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281236 | 0.83 | TGFBR1 (0.79) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30183082 | 0.83 | TGFBR1 (0.79) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281242 | 0.80 | TGFBR1 (0.61) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30182820 | 0.80 | TGFBR1 (0.72) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281243 | 0.80 | TGFBR1 (0.72) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281257 | 0.79 | TGFBR1 (0.71) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29281232 | 0.76 | TGFBR1 (0.80) | TGFBR1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |