SCHEMBL29282745

SCHEMBL29282745

OCCCCCc1cccc(O)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
BID P55957 7/20 0.41
MCL1 Q07820 7/20 0.41
BCL2L1 Q07817 6/20 0.41
BAK1 Q16611 6/20 0.41
KAT8 Q9H7Z6 2/20 0.41
SAE1 Q9UBE0 2/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
MGLL Q99685 1/20 0.40
MMP2 P08253 2/20 0.36
F7 P08709 2/20 0.36
F3 P13726 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574395 0.84 BID (0.59) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL574605 0.84 BID (0.59) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL15995366 0.84 BID (0.59) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL27462450 0.84 BID (0.59) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL573936 0.81 BID (0.57) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL9863155 0.81 IAPP (0.50) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL9863325 0.81 IAPP (0.50) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL8055362 0.80 MGLL (0.58) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL10522207 0.80 MGLL (0.58) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL8618791 0.80 MGLL (0.58) TSHRBIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043024-A Solid composition for dyeing keratin 花王株式会社 2024-05-14 CN disclosed