Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.50 |
| ▸ | BID | P55957 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863325 | 1.00 | IAPP (0.50) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL30810444 | 0.92 | IAPP (0.53) | IAPP | |
| SCHEMBL1236262 | 0.92 | IAPP (0.53) | IAPP | |
| SCHEMBL10414030 | 0.89 | IAPP (0.59) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9153692 | 0.87 | ALOX5 (0.47) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL8055362 | 0.83 | MGLL (0.58) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL13446845 | 0.83 | MGLL (0.58) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL8526141 | 0.83 | MGLL (0.58) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL8618791 | 0.83 | MGLL (0.58) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL10522207 | 0.83 | MGLL (0.58) | BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025036-A | Antiinflammatory agents, gastrointestinal, cardiovascular and skin disorders | HOFFMANN-LA ROCHE INC. (US) | 1991-06-18 | — | — | US | disclosed |