Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4213410 | 0.77 | MAPKAPK2 (0.43) | MAPKAPK2CA1CA2 | |
| SCHEMBL6815208 | 0.74 | RAB9A (0.49) | HTTHPGDALDH1A1MAPKAPK2NPC1 | |
| SCHEMBL3582232 | 0.73 | MAPKAPK2 (0.43) | MAPKAPK2CA1CA2 | |
| SCHEMBL14068644 | 0.71 | CA1 (0.56) | HTTALDH1A1CA1CA2CYP1A2 | |
| SCHEMBL6814997 | 0.70 | KMT2A (0.45) | HTTHPGDALDH1A1MAPKAPK2CA1 | |
| SCHEMBL2928020 | 0.70 | HDAC3 (0.50) | HPGDALDH1A1CA1CA2CYP1A2 | |
| SCHEMBL8571236 | 0.69 | CA12 (0.43) | MAPKAPK2CA1CA2 | |
| SCHEMBL8569699 | 0.68 | TAS1R3 (0.46) | HTTHPGDALDH1A1CA1RAB9A | |
| SCHEMBL24449312 | 0.68 | CA12 (0.45) | HPGDMAPKAPK2CA1CA2NPC1 | |
| SCHEMBL282268 | 0.68 | DHODH (0.45) | HPGDALDH1A1MAPKAPK2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675824-B1 | SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS | WURSTER SIEGFRIED (FI) | 2010-09-29 | — | — | EP | disclosed |
| US-7741362-B2 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | SIEGFRIED WURSTER (FI) | 2010-06-22 | — | — | US | disclosed |
| US-20100004339-A1 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists | OY JUVANTIA PHARMA LTD. (FI) | 2010-01-07 | — | — | US | disclosed |
| US-20070129422-A1 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | OY JUVANTIA PHARMA LTD (FI) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129422-A1 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | SSTR4, SSTR1, SSTR3 | HTT 2132/4885TRPV1 968/4885HPGD 4435/4885 |
| US-20100004339-A1 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists | SSTR4, SSTR1, SSTR3 | HTT 2132/4885TRPV1 968/4885HPGD 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.