Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15154809 | 0.80 | — | — | |
| SCHEMBL1694301 | 0.76 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| Biphenyl SCHEMBL27921340 | 0.74 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2ATMBRD4 | |
| SCHEMBL296516 | 0.69 | ESR1 (0.33) | ALDH1A1MAPTTSHR | |
| SCHEMBL19547982 | 0.69 | ADRA2A (0.43) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2GAA | |
| SCHEMBL18852675 | 0.69 | — | — | |
| SCHEMBL8150674 | 0.68 | CA4 (0.39) | ALDH1A1MEN1KMT2ATSHRMMP9 | |
| SCHEMBL3483654 | 0.68 | — | — | |
| SCHEMBL8638710 | 0.68 | — | — | |
| SCHEMBL12268484 | 0.68 | ESR1 (0.32) | ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140023929-A1 | Silicon-Containing Carbonaceous Composite Material | DOW CORNING TORAY CO., LTD. (JP) | 2014-01-23 | — | — | US | disclosed |
| WO-2013115114-A1 | SILICON-CONTAINING CARBON-BASED COMPOSITE MATERIAL | DOW CORNING TORAY CO., LTD. (JP) | 2013-08-08 | — | — | WO | disclosed |
| EP-1699875-B1 | ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL | DOW CORNING TORAY CO LTD (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-7625986-B2 | Additional-curable organopolysiloxane resin composition and an optical material | DOW CORNING CORPORATION (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080033120-A1 | Additional-Curable Organopolysiloxane Resin Composition and an Optical Material | DOW TORAY CO., LTD. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1699875-A2 | ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL | Dow Corning Toray Co., Ltd. (JP) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005054371-A2 | ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL | DOW CORNING TORAY CO., LTD. (JP) | 2005-06-16 | — | — | WO | disclosed |