SCHEMBL29283240

SCHEMBL29283240

C1#Cc2ccccc2-c2ccccc2C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.35
MAOB P27338 2/20 0.35
CES1 P23141 2/20 0.33
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BCHE P06276 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30
ACHE P22303 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6594792 0.80
SCHEMBL7548249 0.79 MAOA (0.37) MAOAMAOBCES1KDM4ENPC1
SCHEMBL7548244 0.79 MAOA (0.37) MAOAMAOBCES1KDM4ENPC1
SCHEMBL29390452 0.78 CES1 (0.40) MAOAMAOBCES1NPC1HPGD
SCHEMBL504079 0.78 CES1 (0.40) MAOAMAOBCES1NPC1HPGD
SCHEMBL1286828 0.77 MAOA (0.41) MAOAMAOBCES1KDM4ENPC1
Ammonia Solution, Strong SCHEMBL28819102 0.77 CES1 (0.39) MAOAMAOBCES1NPC1HPGD
Ethylene SCHEMBL28524974 0.75 CES1 (0.38) MAOAMAOBCES1HPGDBCHE
Hydrochloric Acid SCHEMBL28015311 0.75 CES1 (0.38) MAOAMAOBCES1KDM4EALDH1A1
SCHEMBL29537848 0.72 CES1 (0.35) MAOAMAOBCES1HPGDCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 CN disclosed