Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548244 | 1.00 | MAOA (0.37) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL8161643 | 0.83 | MAOA (0.54) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL4822665 | 0.82 | SRD5A1 (0.41) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL2144679 | 0.79 | — | — | |
| SCHEMBL9630603 | 0.79 | — | — | |
| SCHEMBL29283240 | 0.79 | MAOA (0.35) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL2285719 | 0.77 | CES1 (0.41) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL2952083 | 0.74 | MAOA (0.44) | MAOAMAOBCES1MAPTHPGD | |
| SCHEMBL3922537 | 0.74 | MAOA (0.42) | MAOAMAOBCES1NPC1RAB9A | |
| SCHEMBL1450361 | 0.71 | MEN1 (0.38) | MAOAMAOBCES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077309-A | Thromboxane a2 antagonist | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-12-31 | — | — | US | claimed |
| US-5055582-A | Process for preparing thromboxane A2 antagonists | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-10-08 | — | — | US | claimed |
| US-5025034-A | Thromboxane inhibitors | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-18 | — | — | US | claimed |
| US-4945106-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-07-31 | — | — | US | claimed |
| EP-0231078-B1 | PROSTAGLANDINS | NAT RES DEV (GB) | 1990-04-25 | — | — | EP | claimed |
| US-4596823-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-06-24 | — | — | US | claimed |
| EP-0819981-B1 | Radiation sensitive resin composition | JSR CORP (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5952150-A | COMPRISING A DISULFONYLMETHANE DERIVATIVE, A RESIN PROTECTED BY AN ACID DECOMPOSABLE GROUP OR AN ALKALI-SOLUBLE RESIN AND AN ALKALI SOLUBILITY CONTROL AGENT; PHOTORESISTS | JSR CORPORATION (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0819981-A1 | Radiation sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5055582-A | Process for preparing thromboxane A2 antagonists | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-10-08 | — | — | US | disclosed |
| US-4992563-A | Benzopyran intermediates for use in manufacturing thromboxane A2 antagonists | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0231078-B1 | PROSTAGLANDINS | NAT RES DEV (GB) | 1990-04-25 | — | — | EP | disclosed |