Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.64 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283815 | 0.88 | HSP90AB1 (0.48) | HSP90AB1GRM2PTPRCPTPN1TNKS | |
| SCHEMBL31006510 | 0.88 | HSP90AB1 (0.48) | HSP90AB1GRM2PTPRCPTPN1TNKS | |
| SCHEMBL29283851 | 0.86 | HSP90AB1 (0.64) | HSP90AB1GRM2DAOCASRMETAP2 | |
| SCHEMBL29283865 | 0.85 | HSP90AB1 (0.69) | HSP90AB1GRM2CASRHDAC6METAP2 | |
| SCHEMBL31006511 | 0.85 | HSP90AB1 (0.60) | HSP90AB1GRM2CASRHDAC6ACHE | |
| SCHEMBL29283801 | 0.85 | HSP90AB1 (0.60) | HSP90AB1GRM2CASRHDAC6ACHE | |
| SCHEMBL31006527 | 0.85 | HSP90AB1 (0.76) | HSP90AB1GRM2CASRHDAC6METAP2 | |
| SCHEMBL29283806 | 0.85 | HSP90AB1 (0.76) | HSP90AB1GRM2CASRHDAC6METAP2 | |
| SCHEMBL31006508 | 0.83 | HSP90AB1 (0.67) | HSP90AB1GRM2CASRHDAC6METAP2 | |
| SCHEMBL29283810 | 0.83 | HSP90AB1 (0.67) | HSP90AB1GRM2CASRHDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |