Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | DHPS | P49366 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283815 | 1.00 | HSP90AB1 (0.48) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL29283874 | 0.88 | HSP90AB1 (0.64) | HSP90AB1PTPRCPTPN1GRM2TNKS | |
| SCHEMBL29283849 | 0.88 | THRB (0.45) | HSP90AB1LMNATP53PTPRCPTPN1 | |
| SCHEMBL31006533 | 0.85 | HSP90AB1 (0.48) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL29283840 | 0.85 | HSP90AB1 (0.48) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL29283875 | 0.85 | HSP90AB1 (0.53) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL31006525 | 0.85 | HSP90AB1 (0.53) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL29283829 | 0.84 | HSP90AB1 (0.46) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL31006558 | 0.84 | HSP90AB1 (0.46) | HSP90AB1DHPSLMNAROCK2ROCK1 | |
| SCHEMBL31006516 | 0.84 | HSP90AB1 (0.57) | HSP90AB1DHPSROCK2ROCK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |