Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283801 | 1.00 | HSP90AB1 (0.60) | HSP90AB1HDAC6TRPA1GRM2SLC13A5 | |
| SCHEMBL29283829 | 0.89 | HSP90AB1 (0.46) | HSP90AB1TRPA1GRM2PPARGPPARA | |
| SCHEMBL31006558 | 0.89 | HSP90AB1 (0.46) | HSP90AB1TRPA1GRM2PPARGPPARA | |
| SCHEMBL29283874 | 0.85 | HSP90AB1 (0.64) | HSP90AB1HDAC6GRM2ACHEFFAR1 | |
| SCHEMBL29283817 | 0.84 | HSP90AB1 (0.65) | HSP90AB1HDAC6GRM2BACE1ACHE | |
| SCHEMBL31006522 | 0.84 | HSP90AB1 (0.65) | HSP90AB1HDAC6GRM2BACE1ACHE | |
| SCHEMBL29283851 | 0.83 | HSP90AB1 (0.64) | HSP90AB1GRM2CASR | |
| SCHEMBL31006513 | 0.82 | HSP90AB1 (0.66) | HSP90AB1HDAC6GRM2SLC13A5ACHE | |
| SCHEMBL29283836 | 0.82 | HSP90AB1 (0.66) | HSP90AB1HDAC6GRM2SLC13A5ACHE | |
| SCHEMBL31006527 | 0.82 | HSP90AB1 (0.76) | HSP90AB1HDAC6GRM2BACE1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |