Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | FURIN | P09958 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 8/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284554 | 0.87 | MAP1LC3B (0.40) | MAP1LC3BFURINHRH1KLKB1TP53 | |
| SCHEMBL29284547 | 0.85 | NPC1 (0.41) | MAP1LC3BHTT | |
| SCHEMBL20513041 | 0.79 | HTT (0.44) | FURINHTT | |
| SCHEMBL20513040 | 0.79 | HTT (0.44) | FURINHTT | |
| SCHEMBL29284569 | 0.79 | NPC1 (0.41) | MAP1LC3BHTT | |
| SCHEMBL29284586 | 0.79 | NPC1 (0.41) | MAP1LC3BHTT | |
| SCHEMBL22068098 | 0.78 | NPC1 (0.40) | MAP1LC3BHTT | |
| SCHEMBL21781878 | 0.78 | MAP1LC3B (0.37) | MAP1LC3BFURINHRH1KLKB1FAP | |
| SCHEMBL22068096 | 0.77 | NPC1 (0.41) | MAP1LC3BHTT | |
| SCHEMBL17595585 | 0.77 | FURIN (0.44) | FURINHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312730-B | Cytotoxins and conjugates, uses thereof and methods of preparation | 四川科伦博泰生物医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |