Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284688 | 0.86 | — | — | |
| SCHEMBL29284673 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2KMT2AKDM6B | |
| Hydrochloric Acid SCHEMBL29284675 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2KMT2AKDM6B | |
| SCHEMBL29284670 | 0.79 | MAPT (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29284685 | 0.73 | CYP3A4 (0.34) | — | |
| SCHEMBL713246 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2PTGER4 | |
| SCHEMBL15484319 | 0.71 | NR4A3 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29284672 | 0.71 | PTGS2 (0.30) | — | |
| SCHEMBL29284665 | 0.69 | — | — | |
| SCHEMBL29284657 | 0.68 | POLB (0.31) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206533-A | N-pyridazine pyrazole amide compounds | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118206533-A | N-pyridazine pyrazole amide compounds | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | disclosed |