Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 4/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284763 | 0.81 | PTGES (0.36) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL29284761 | 0.72 | HSD17B10 (0.38) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL29284757 | 0.72 | PDE2A (0.38) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL29284765 | 0.68 | FGFR1 (0.43) | FGFR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30963687 | 0.68 | FGFR1 (0.43) | FGFR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29284758 | 0.67 | PIK3CA (0.38) | KDM4EL3MBTL1 | |
| SCHEMBL21917497 | 0.67 | MAPT (0.51) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL10883857 | 0.67 | FGFR1 (0.43) | FGFR1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL21717819 | 0.66 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL28988465 | 0.66 | KDM4E (0.56) | ALDH1A1KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221684-A | Method for preparing quinoxaline derivative through HFIP-promoted defluorination cyclization reaction of difluoro carbene reagent | 陕西科技大学 | 2024-06-21 | — | — | CN | disclosed |