Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839470 | 0.82 | PRMT5 (0.45) | ALDH1A1SLC6A3ATMCYP4F2CYP4A11 | |
| SCHEMBL10311104 | 0.82 | PRMT5 (0.45) | ALDH1A1SLC6A3ATMCYP4F2CYP4A11 | |
| SCHEMBL5390528 | 0.81 | KMO (0.59) | ALDH1A1MAPK1ATMCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL10277298 | 0.81 | PRMT5 (0.45) | ALDH1A1SLC6A3ATMCYP4F2CYP4A11 | |
| SCHEMBL1790402 | 0.80 | KMO (0.61) | ALDH1A1MAPK1ATMCYP4F2CYP4A11 | |
| SCHEMBL21806476 | 0.80 | CA12 (0.49) | ALDH1A1NPC1RAB9A | |
| SCHEMBL231497 | 0.79 | MAPT (0.48) | ALOX5ATM | |
| SCHEMBL1273971 | 0.78 | HTR2C (0.54) | ATMCYP4F2CYP4A11KDM4ENPC1 | |
| SCHEMBL28781927 | 0.78 | CYP2C19 (0.51) | ALDH1A1MAPK1ATMALOX15SMN1; SMN2 | |
| SCHEMBL10311097 | 0.77 | CHRNB2 (0.46) | ALDH1A1ALOX15NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265696-A | Aryl carboxylic acid compound and application thereof in preparation of Mrgpr X < 4 > inhibitor | 深圳博瑞医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |