Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786481 | 0.76 | BRD4 (0.35) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL20577534 | 0.72 | AXL (0.37) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL21725762 | 0.70 | BRD4 (0.33) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL24613002 | 0.70 | BRD4 (0.33) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL1014315 | 0.69 | ERN1 (0.39) | LMNAERN1KDM4EMETAP2TDP1 | |
| SCHEMBL25241637 | 0.69 | AXL (0.37) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL2425808 | 0.69 | LMNA (0.41) | LMNAERN1KDM4EALDH1A1HPGD | |
| SCHEMBL21196014 | 0.68 | HTT (0.35) | KDM4EALDH1A1HPGDBRD4METAP2 | |
| SCHEMBL31166894 | 0.68 | ALDH1A1 (0.42) | MCL1ERN1KDM4EALDH1A1TSHR | |
| SCHEMBL4655024 | 0.68 | ALDH1A1 (0.42) | MCL1ERN1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |