Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762302 | 0.85 | BRAF (0.49) | BRAF | |
| SCHEMBL2932065 | 0.82 | BRAF (0.52) | BRAF | |
| SCHEMBL9909761 | 0.80 | BRAF (0.52) | BRAF | |
| SCHEMBL2931685 | 0.79 | BRAF (0.63) | BRAF | |
| SCHEMBL15911745 | 0.75 | BRAF (0.46) | BRAF | |
| SCHEMBL2928507 | 0.74 | BRAF (0.71) | BRAF | |
| SCHEMBL2931472 | 0.73 | BRAF (0.49) | BRAF | |
| SCHEMBL2927751 | 0.73 | BRAF (0.57) | BRAF | |
| SCHEMBL2932795 | 0.72 | BRAF (0.56) | BRAF | |
| SCHEMBL3756201 | 0.72 | BRAF (0.60) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229391-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077766-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |