SCHEMBL29285201

SCHEMBL29285201

C(=C/c1ccccc1)\CNc1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
MAOB P27338 1/20 0.45
HDAC1 Q13547 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
IDO1 P14902 2/20 0.40
PAM P19021 1/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HDAC2 Q92769 1/20 0.40
NPC1 O15118 1/20 0.40
MITF O75030 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DHFR P00374 1/20 0.39
PRMT1 Q99873 1/20 0.39
FFAR1 O14842 1/20 0.39
CA1 P00915 1/20 0.39
MGLL Q99685 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29285202 1.00 KDM4E (0.45) KDM4EMAOBHDAC1FNTAFNTB
SCHEMBL6665965 0.88 MAOB (0.55) KDM4EMAOBIDO1PAMRAB9A
SCHEMBL10748019 0.88 MAOB (0.55) KDM4EMAOBIDO1PAMRAB9A
SCHEMBL1065321 0.84 MAOB (0.44) KDM4EMAOBIDO1PAMRAB9A
SCHEMBL20651287 0.84 NFE2L2 (0.53) KDM4EMAOBRAB9AALDH1A1NPC1
SCHEMBL1065322 0.84 MAOB (0.44) KDM4EMAOBIDO1PAMRAB9A
SCHEMBL693125 0.84 MAOB (0.53) KDM4EMAOBIDO1RAB9AALDH1A1
SCHEMBL28981267 0.84 EGFR (0.53) KDM4EMAOBRAB9AALDH1A1NPC1
SCHEMBL28981265 0.84 EGFR (0.53) KDM4EMAOBRAB9AALDH1A1NPC1
SCHEMBL22861517 0.80 RAB9A (0.62) MAOBRAB9AALDH1A1NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271180-A Preparation method of allylamine compound 大连理工大学 2024-07-02 CN disclosed