Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702996 | 0.98 | LMNA (0.44) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL16538611 | 0.95 | GPR119 (0.45) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL16538625 | 0.95 | GPR119 (0.45) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL7414912 | 0.94 | GPR119 (0.43) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL7414916 | 0.94 | GPR119 (0.43) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL143674 | 0.91 | LMNA (0.47) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL345625 | 0.91 | LMNA (0.47) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL86666 | 0.91 | LMNA (0.47) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL4093277 | 0.88 | NPSR1 (0.44) | LMNANPSR1MEN1KMT2AAPP | |
| SCHEMBL25319775 | 0.88 | GPR119 (0.47) | LMNANPSR1MEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324715-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117750962-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-03-22 | — | — | CN | disclosed |