Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20731991 | 1.00 | MAPK1 (0.37) | MAPK1PTGS2ALDH1A1HDAC8AKT3 | |
| SCHEMBL20722978 | 0.82 | USP2 (0.47) | ALDH1A1RECQL | |
| SCHEMBL20722980 | 0.82 | USP2 (0.47) | ALDH1A1RECQL | |
| SCHEMBL29223124 | 0.77 | PTGS2 (0.41) | MAPK1PTGS2ALDH1A1CASR | |
| SCHEMBL2895608 | 0.77 | HDAC8 (0.56) | HDAC8 | |
| SCHEMBL3751401 | 0.77 | HDAC8 (0.56) | HDAC8 | |
| SCHEMBL2895605 | 0.77 | HDAC8 (0.56) | HDAC8 | |
| SCHEMBL23387519 | 0.75 | HDAC8 (0.48) | ALDH1A1HDAC8 | |
| Hydrochloric Acid SCHEMBL3740720 | 0.75 | HDAC8 (0.58) | HDAC8 | |
| Hydrochloric Acid SCHEMBL3751396 | 0.75 | HDAC8 (0.58) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |