Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | ATF1 | P18846 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29223237 | 0.79 | PIN1 (0.33) | ALDH1A1 | |
| SCHEMBL20732114 | 0.78 | PTGS2 (0.41) | PTGS2ALDH1A1KIF11MAPT | |
| SCHEMBL30060129 | 0.78 | PTGS2 (0.41) | PTGS2ALDH1A1KIF11MAPT | |
| SCHEMBL28586342 | 0.78 | PTGS2 (0.41) | PTGS2ALDH1A1KIF11MAPT | |
| SCHEMBL4767426 | 0.78 | KMT2A (0.41) | ALDH1A1NFKB1LMNA | |
| SCHEMBL20731991 | 0.77 | MAPK1 (0.37) | PTGS2ALDH1A1MAPK1CASR | |
| SCHEMBL29286113 | 0.77 | MAPK1 (0.37) | PTGS2ALDH1A1MAPK1CASR | |
| SCHEMBL4773802 | 0.77 | L3MBTL1 (0.48) | LMNA | |
| SCHEMBL4766678 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPTTDP1 | |
| SCHEMBL4770069 | 0.76 | ATF1 (0.41) | ALDH1A1MAPK1SYKNFKB1ATF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917406-A | Heterocyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2024-04-23 | — | — | CN | disclosed |