SCHEMBL29286158

SCHEMBL29286158

Cc1ccc2ccc3cnc(N)nc3c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 2/20 0.57
DYRK1A Q13627 1/20 0.57
CDK5 Q00535 1/20 0.41
CDK5R1 Q15078 1/20 0.41
CYP1A2 P05177 3/20 0.40
CYP2A6 P11509 3/20 0.40
EGFR P00533 1/20 0.40
TYMS P04818 1/20 0.39
ADORA1 P30542 1/20 0.39
CCR1 P32246 1/20 0.38
CCR5 P51681 1/20 0.38
CCR8 P51685 1/20 0.38
NCK1 P16333 1/20 0.38
BACE1 P56817 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968858 1.00 CLK1 (0.57) CLK1DYRK1ACDK5CDK5R1CYP1A2
SCHEMBL30968859 1.00 CLK1 (0.57) CLK1DYRK1ACDK5CDK5R1CYP1A2
SCHEMBL24473240 0.79 CYP1A2 (0.40) CLK1DYRK1ACYP1A2CYP2A6TYMS
SCHEMBL22136018 0.76 CLK1 (0.62) CLK1DYRK1ACDK5CDK5R1CYP2A6
SCHEMBL22449721 0.76 CYP1A2 (0.50) CLK1DYRK1ACYP1A2CYP2A6ADORA1
SCHEMBL2632884 0.72 LCK (0.57) CLK1DYRK1ACYP1A2CYP2A6ADORA1
SCHEMBL12490217 0.70 NOS3 (0.41) CYP1A2CYP2A6TYMSCCR1CCR5
SCHEMBL13591993 0.69 CLK1 (0.54) CLK1DYRK1ACDK5CDK5R1KDM4E
SCHEMBL2918287 0.69 CLK1 (0.46) CLK1DYRK1ACDK5CDK5R1FGFR1
SCHEMBL599276 0.68 CYP1A2 (0.65) CYP1A2CYP2A6TYMSNCK1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344864-A Application of multi-nitrogen heterocyclic triphenylamine compound as luminescent material 江苏省计量科学研究院(江苏省能源计量数据中心) 2024-07-16 CN disclosed