SCHEMBL29286159

SCHEMBL29286159

CC(C)c1cccc(C(C)C)c1N1C(=O)c2cccc(c2)C1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 5/20 0.58
DPP4 P27487 5/20 0.58
NR1H2 P55055 1/20 0.53
NR1H3 Q13133 1/20 0.53
FAAH O00519 2/20 0.41
MGLL Q99685 1/20 0.41
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
GABRA1 P14867 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
GABRB1 P18505 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15437793 0.84 DPP4 (0.55) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL2820118 0.79 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL29366407 0.79 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL30954668 0.78 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL17531021 0.78 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL6925321 0.77 ANPEP (0.66) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL9612014 0.76 DPP4 (0.63) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL2481189 0.75 DPP4 (0.80) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL125918 0.75 DPP4 (0.59) ANPEPDPP4NR1H2NR1H3FAAH
SCHEMBL13171786 0.75 ANPEP (0.71) ANPEPDPP4NR1H2NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344291-A Method for preparing imide by rearrangement of isoamide and application thereof 中国石油化工股份有限公司 2024-07-16 CN disclosed