Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18992448 | 0.91 | HSD17B10 (0.37) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL20168082 | 0.91 | HSD17B10 (0.37) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL18992446 | 0.91 | HSD17B10 (0.37) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL18992262 | 0.84 | CA14 (0.36) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL18992260 | 0.84 | CA14 (0.36) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL29286303 | 0.81 | CA14 (0.33) | CA14ITGB3ITGA2B | |
| SCHEMBL19000778 | 0.80 | ALDH1A1 (0.41) | CA14HSD17B10SMN1; SMN2 | |
| SCHEMBL25193443 | 0.78 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2DPP4DPP8DPP9 | |
| SCHEMBL31296240 | 0.78 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2DPP4DPP8DPP9 | |
| SCHEMBL16528528 | 0.78 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069489-A | Diamino-alkylamino linked arylsulfonamide compounds having selective activity for voltage-gated sodium channels | 默沙东公司 | 2018-12-21 | — | — | CN | disclosed |