Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31296240 | 1.00 | HSD17B10 (0.38) | HSD17B10CYP2D6DPP4DPP8DPP9 | |
| SCHEMBL16528528 | 1.00 | HSD17B10 (0.38) | HSD17B10CYP2D6DPP4DPP8DPP9 | |
| SCHEMBL28464173 | 0.86 | HSD17B10 (0.36) | HSD17B10SMN1; SMN2HTR2CSLC6A4POLB | |
| SCHEMBL34474623 | 0.79 | PREP (0.47) | HTR2CSLC6A4L3MBTL1LMNA | |
| SCHEMBL30511005 | 0.79 | PREP (0.47) | HTR2CSLC6A4L3MBTL1LMNA | |
| SCHEMBL31509972 | 0.78 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL29286314 | 0.78 | CA14 (0.35) | HSD17B10CYP2D6DPP4DPP8DPP9 | |
| SCHEMBL3295966 | 0.77 | OPRK1 (0.46) | HSD17B10DPP4POLBL3MBTL1LMNA | |
| SCHEMBL5412332 | 0.77 | OPRK1 (0.46) | HSD17B10DPP4POLBL3MBTL1LMNA | |
| SCHEMBL5412325 | 0.77 | OPRK1 (0.46) | HSD17B10DPP4POLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086438-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |