Sarcosine

Sarcosine

SCHEMBL29286554

CNCC(=O)O.N#CC#N

nearest known ligand 0.39

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.39
CTH P32929 1/20 0.37
EGLN1 Q9GZT9 3/20 0.36
APEX1 P27695 1/20 0.35
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FFAR3 O14843 1/20 0.33
KDM4E B2RXH2 1/20 0.32
KDM5C P41229 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
ECE1 P42892 1/20 0.30
CYP2D6 P10635 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarcosine SCHEMBL26675067 0.92
Sarcosine SCHEMBL2327706 0.92 MCL1 (0.37) MCL1CTHEGLN1APEX1LDHA
Sarcosine SCHEMBL8907159 0.91
Sarcosine SCHEMBL8744852 0.90
Sarcosine SCHEMBL22689538 0.88
Sarcosine SCHEMBL156329 0.88 LDHA (0.44) CTHEGLN1APEX1LDHASRR
Sarcosine SCHEMBL28259932 0.88
Sarcosine SCHEMBL31427574 0.88
Sarcosine SCHEMBL149 0.88
Sarcosine SCHEMBL26641423 0.88 LDHA (0.44) CTHEGLN1APEX1LDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104854117-B Process for the synthesis of N-phosphonomethyliminodiacetic acid 孟山都技术有限责任公司 2018-12-25 CN disclosed