Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Sarcosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sarcosine SCHEMBL22689538 | 0.97 | — | — | |
| Sarcosine SCHEMBL149 | 0.97 | — | — | |
| Sarcosine SCHEMBL26641423 | 0.97 | LDHA (0.44) | — | |
| Sarcosine SCHEMBL28259932 | 0.97 | — | — | |
| Sarcosine SCHEMBL31427574 | 0.97 | — | — | |
| Sarcosine SCHEMBL156329 | 0.97 | LDHA (0.44) | — | |
| Sarcosine SCHEMBL19463208 | 0.94 | — | — | |
| Sarcosine SCHEMBL23041026 | 0.93 | — | — | |
| Sarcosine SCHEMBL20608183 | 0.93 | — | — | |
| Sarcosine SCHEMBL20582854 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118225545-A | Recombinant human TNF-alpha protein freeze-dried pellet and preparation method and application thereof | 江西赛基生物技术有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-109957533-A | One plant of marine bacteria for producing sarcosine oxidase and its application | 大连大学 | 2019-07-02 | — | — | CN | claimed |
| CN-109715799-A | Modified sarcosine oxidase and its gene and manufacturing method | 龟甲万株式会社 | 2019-05-03 | — | — | CN | claimed |
| CN-106770588-B | A kind of sarcosine detection device and preparation method thereof, application | 深圳大学 | 2019-04-16 | — | — | CN | claimed |
| CN-118225545-B | Recombinant human TNF-alpha protein freeze-dried pellet and preparation method and application thereof | 江西赛基生物技术有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118225545-A | Recombinant human TNF-alpha protein freeze-dried pellet and preparation method and application thereof | 江西赛基生物技术有限公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2024034580-A1 | METHOD FOR DETECTING CEACAM1 | 株式会社先端生命科学研究所 | 2024-02-15 | — | — | WO | disclosed |
| CN-115379833-A | Transdermal osmotic agent preparation containing cannabidiol | 黛芙生物科学公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115379859-A | Transdermal osmotic agent formulation | 黛芙生物科学公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109957538-A | A kind of genetic engineering bacterium and its preparation method and application preparing sarcosine oxidase | 大连大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-109897805-A | A kind of screening technique producing sarcosine oxidase bacterial strain | 大连大学 | 2019-06-18 | — | — | CN | disclosed |
| CN-106290329-B | A kind of application of polymer and the composition for stablizing enzyme and color developing agent | 三诺生物传感股份有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-106290329-A | The application of a kind of polymer and stablize the compositions of enzyme and developer | 三诺生物传感股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-103238063-B | Electrode for electrochemical measurement, electrochemical gaging electrolyzer and electrochemical gaging analytical equipment and their manufacture method | 株式会社日立高新技术 | 2016-12-21 | — | — | CN | disclosed |
| CN-104853722-A | ORAL CARE PRODUCTS COMPRISING TETRABASIC ZINC CHLORIDE AND TRIMETHYLGLYCINE | COLGATE PALMOLIVE CO | 2015-08-19 | — | — | CN | disclosed |
| CN-100457182-C | Behavior chemotherapy | BE ABLE LLC (US) | 2009-02-04 | — | — | CN | disclosed |
| CN-1950073-A | Nutritional composition for increasing creatine uptake in skeletal muscle | THERMO FORMULATIONS LTD (CA) | 2007-04-18 | — | — | CN | disclosed |
| CN-1461222-A | behavioral chemotherapy | BE ABLE LLC (US) | 2003-12-10 | — | — | CN | disclosed |
| EP-0760677-A1 | A PHARMACEUTICAL PREPARATION COMPRISING GLUCAGON | NOVO NORDISK A/S (DK) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032730-A1 | A PHARMACEUTICAL PREPARATION COMPRISING GLUCAGON | NOVO NORDISK A/S (DK) | 1995-12-07 | — | — | WO | disclosed |