Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240921 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL17033995 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL21031531 | 0.79 | MAOA (0.52) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL18708347 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAALDH1A1HPGDMAPT | |
| SCHEMBL10614463 | 0.75 | ELANE (0.47) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL25847833 | 0.74 | ESR1 (0.44) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL25847178 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL21032077 | 0.73 | MEN1 (0.40) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL25847867 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL19169219 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256451-B | Synthetic method of benzofuro [2,3-b ] quinoline derivative | 河南省科学院化学研究所有限公司 | 2021-09-03 | — | — | CN | disclosed |