Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24241924 | 1.00 | MEN1 (0.45) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL12040557 | 0.81 | LMNA (0.57) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL22084146 | 0.80 | MEN1 (0.42) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL29287203 | 0.80 | MEN1 (0.42) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL29287205 | 0.79 | HSD11B1 (0.48) | MEN1KMT2ARAB9ALMNAHSD11B1 | |
| SCHEMBL22084145 | 0.79 | HSD11B1 (0.48) | MEN1KMT2ARAB9ALMNAHSD11B1 | |
| SCHEMBL22084148 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL31683580 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL31525726 | 0.78 | MAOB (0.55) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL22027031 | 0.77 | LMNA (0.40) | MEN1KMT2ARAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250281515-A1 | CARBORANE COMPOUNDS, CARBORANE ANALOGS, AND METHODS OF USE THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2025-09-11 | — | — | US | disclosed |
| CN-113347979-B | Carborane compounds, carborane analogs, and methods of use thereof | 俄亥俄州创新基金会 | 2024-08-16 | — | — | CN | disclosed |
| CN-113347979-A | Carborane compounds, carborane analogs, and methods of use thereof | 俄亥俄州创新基金会 | 2021-09-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250281515-A1 | CARBORANE COMPOUNDS, CARBORANE ANALOGS, AND METHODS OF USE THEREOF | ESR2, ESRRB, ESRRA | MEN1 3195/4885KMT2A 1657/4885RAB9A 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.