SCHEMBL29287232

SCHEMBL29287232

CCCCCCCCC(N)(Cl)C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
NAAA Q02083 1/20 0.46
KCNH2 Q12809 1/20 0.42
GAA P10253 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
S1PR5 Q9H228 1/20 0.41
SMPD1 P17405 2/20 0.41
FDPS P14324 1/20 0.41
SCN5A Q14524 3/20 0.41
SCN9A Q15858 3/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29726624 0.84 CES1 (0.50) CES2CES1NAAAKCNH2GAA
SCHEMBL9632450 0.84 CES1 (0.50) CES2CES1NAAAKCNH2GAA
SCHEMBL20379017 0.82 CES1 (0.49) CES2CES1NAAAKCNH2GAA
SCHEMBL15993577 0.81 CES2 (0.47) CES2CES1NAAAKCNH2GAA
Ammonia Solution, Strong SCHEMBL27806818 0.81 CES2 (0.47) CES2CES1NAAAKCNH2GAA
SCHEMBL1532739 0.81 CES1 (0.47) CES2CES1NAAAKCNH2GAA
SCHEMBL11416528 0.81 CES1 (0.47) CES2CES1NAAAKCNH2GAA
SCHEMBL11782068 0.79 CES1 (0.51) CES2CES1NAAAKCNH2GAA
SCHEMBL30716568 0.79 CES2 (0.51) CES2CES1NAAAKCNH2GAA
SCHEMBL11664524 0.79 CES1 (0.51) CES2CES1NAAAKCNH2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195599-A antifungal composition 株式会社种探索研究所 2019-01-11 CN disclosed