Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 10/20 | 0.45 |
| ▸ | AURKA | O14965 | 8/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.38 |
| ▸ | CCND1 | P24385 | 5/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640940 | 0.78 | CCND1 (0.60) | CDK4CDK1CDK6CCND1CCNE1 | |
| SCHEMBL19857389 | 0.78 | CCND1 (0.60) | CDK4CDK1CDK6CCND1CCNE1 | |
| SCHEMBL12631831 | 0.75 | AURKA (0.55) | CDK4AURKACDK1AURKBCDK6 | |
| SCHEMBL4202568 | 0.75 | CDK4 (0.47) | TTKCDK4AURKACDK1INSR | |
| SCHEMBL8513398 | 0.75 | AURKA (0.46) | TTKCDK4AURKACDK1INSR | |
| SCHEMBL29287418 | 0.74 | AURKA (0.46) | TTKCDK4AURKACDK1INSR | |
| SCHEMBL29779671 | 0.74 | AURKA (0.46) | TTKCDK4AURKACDK1INSR | |
| SCHEMBL29990591 | 0.73 | CCND1 (0.56) | CDK4CDK1CDK6CCND1CCNE1 | |
| SCHEMBL586028 | 0.72 | AURKA (0.46) | TTKCDK4AURKACDK1INSR | |
| SCHEMBL8511314 | 0.71 | TTK (0.45) | TTKCDK4AURKACDK1INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749259-B | A kind of synthetic method of cyclopenta pyrimido azoles | 华东师范大学 | 2019-02-01 | — | — | CN | disclosed |