SCHEMBL29287489

SCHEMBL29287489

Ic1ccc(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
NR3C1 P04150 1/20 0.37
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.36
NR4A2 P43354 2/20 0.35
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
AVPR1A P37288 1/20 0.34
LDHA P00338 1/20 0.34
KMT2A Q03164 2/20 0.33
ALOX5 P09917 1/20 0.33
JAK2 O60674 1/20 0.33
IL1R1 P14778 1/20 0.33
CAMKK2 Q96RR4 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24736252 0.95 L3MBTL1 (0.52) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL20005356 0.92 L3MBTL1 (0.43) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL3382322 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL12342482 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL19037041 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL17621896 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL17854701 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL17621889 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL2883793 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL17206541 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMNR3C1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109251195-A A kind of general formula compound and its application in luminous organic material 北京鼎材科技有限公司 2019-01-22 CN disclosed