SCHEMBL3382322

SCHEMBL3382322

Ic1ccc2c(c1)c1cc(-c3ccccc3)ccc1n2-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
ATM Q13315 2/20 0.46
KDM4E B2RXH2 2/20 0.46
AVPR1A P37288 1/20 0.37
KMT2A Q03164 3/20 0.36
IL1R1 P14778 1/20 0.36
DNMT1 P26358 1/20 0.35
TSPO P30536 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HTT P42858 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 1/20 0.35
NR4A2 P43354 2/20 0.35
FAAH O00519 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PKM P14618 1/20 0.34
MGLL Q99685 1/20 0.34
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
LDHA P00338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041563 0.97 L3MBTL1 (0.48) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17658828 0.92 L3MBTL1 (0.58) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL29287489 0.92 L3MBTL1 (0.42) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL16500770 0.90 ATM (0.38) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL29589862 0.89 KDM4E (0.56) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL45663 0.89 KDM4E (0.56) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL18717936 0.89 ATM (0.56) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL16482602 0.89 ATM (0.56) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL11981029 0.89 ATM (0.56) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL18804997 0.89 ATM (0.56) L3MBTL1ATMKDM4EAVPR1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085382-B1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO (JP) 2016-04-20 EP disclosed
US-8895159-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 US disclosed
US-8895159-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 US disclosed
US-8580393-B2 Polymer and organic electroluminescent device including the same IDEMITSU KOSAN CO., LTD. (JP) 2013-11-12 US disclosed
US-20130187137-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-07-25 US disclosed
US-20130187137-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-07-25 US disclosed
US-8394510-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-03-12 US disclosed
US-8394510-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-03-12 US disclosed
US-8283055-B2 Material for light-emitting element, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 US disclosed
US-8283055-B2 Material for light-emitting element, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 US disclosed
US-8283055-B2 Material for light-emitting element, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 US disclosed
US-20110017983-A1 POLYMER AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME IDEMITSU KOSAN CO., LTD. 2011-01-27 US disclosed
US-20100096981-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-22 US disclosed
US-20100096981-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-22 US disclosed
US-20100096981-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-22 US disclosed
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-29 US disclosed
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, AOC2 L3MBTL1 1372/4885ATM 763/4885KDM4E 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.