Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923471 | 0.85 | SMN1; SMN2 (0.35) | HTTPOLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL2929120 | 0.84 | HTT (0.36) | HTTPOLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL2929857 | 0.81 | POLB (0.31) | HTTPOLB | |
| SCHEMBL14401656 | 0.80 | POLB (0.36) | HTTPOLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL2923168 | 0.78 | HTT (0.42) | HTTPOLB | |
| SCHEMBL2929425 | 0.76 | MAPT (0.32) | — | |
| SCHEMBL13356658 | 0.70 | HTT (0.36) | HTTPOLBCNR1CNR2 | |
| SCHEMBL2930475 | 0.69 | SMN1; SMN2 (0.39) | HTTPOLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL4180955 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL8920797 | 0.67 | ALDH1A1 (0.36) | HTTPOLBCNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1733713-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone dervative, a coupling agent and a selected surface-active agent | OREAL (FR) | 2010-06-02 | — | — | EP | disclosed |
| EP-1733716-B1 | Composition for dyeing keratin fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and an associative polyurethane polymer | OREAL (FR) | 2010-05-19 | — | — | EP | disclosed |
| EP-1733714-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a polyol | OREAL (FR) | 2010-05-19 | — | — | EP | disclosed |
| EP-1733715-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a heterocyclic direct dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728500-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728499-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | OREAL (FR) | 2010-01-06 | — | — | EP | disclosed |
| EP-1550656-B1 | fused 4-5-diamino-n,n-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | OREAL (FR) | 2009-05-06 | — | — | EP | disclosed |
| EP-1764082-A2 | 4-5-diamino-N,N-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | L'OREAL (FR) | 2007-03-21 | — | — | EP | disclosed |
| EP-1733713-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone dervative, a coupling agent and a selected surface-active agent | L'OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1733715-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a heterocyclic direct dye | L'OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1733714-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a polyol | L'OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1733716-A1 | Composition for dyeing keratin fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and an associative polyurethane polymer | L'OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1728499-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1550656-A1 | 4-5-diamino-n,n-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | L'OREAL (FR) | 2005-07-06 | — | — | EP | disclosed |