Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929120 | 0.85 | HTT (0.36) | POLBHTTCNR1CNR2SMN1; SMN2 | |
| SCHEMBL2928781 | 0.80 | HTT (0.33) | POLBHTTCNR1CNR2SMN1; SMN2 | |
| SCHEMBL2929857 | 0.80 | POLB (0.31) | POLBHTTLMNA | |
| SCHEMBL1074567 | 0.77 | SMN1; SMN2 (0.37) | POLBHTTCNR1CNR2SMN1; SMN2 | |
| SCHEMBL1026866 | 0.76 | KDM4E (0.45) | POLBHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5383506 | 0.75 | PKM (0.44) | CNR1CNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27603443 | 0.72 | SMN1; SMN2 (0.40) | CNR1CNR2SMN1; SMN2 | |
| SCHEMBL14401659 | 0.72 | HTT (0.37) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8920797 | 0.71 | ALDH1A1 (0.36) | POLBHTTCNR1CNR2SMN1; SMN2 | |
| SCHEMBL5409719 | 0.71 | SMN1; SMN2 (0.41) | POLBHTTCNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285137-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | disclosed |