Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547895 | 0.82 | MAPT (0.61) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL6865448 | 0.80 | MAPT (0.59) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL17605940 | 0.75 | MAPT (0.58) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL17845069 | 0.72 | APP (0.48) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL2519799 | 0.72 | TSHR (0.52) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL2801832 | 0.72 | TSHR (0.52) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL28440820 | 0.72 | ALOX5 (0.38) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL28924102 | 0.71 | MAPT (0.50) | MAPTHTTALDH1A1PKMHPGD | |
| SCHEMBL6960029 | 0.71 | — | — | |
| SCHEMBL7440903 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461501-A | Green method for high-selectivity synthesis of chalcone compounds | 温州大学 | 2021-10-01 | — | — | CN | disclosed |