Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6504930 | 0.99 | RAD52 (0.40) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| Hydrochloric Acid SCHEMBL6095736 | 0.95 | RAD52 (0.39) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| SCHEMBL2926286 | 0.88 | RAD52 (0.42) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| Hydrochloric Acid SCHEMBL6496609 | 0.87 | RAD52 (0.41) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| SCHEMBL2928752 | 0.82 | FFAR1 (0.38) | RAD52GAAFFAR1PPARGKDM4E | |
| Hydrochloric Acid SCHEMBL6505075 | 0.81 | FFAR1 (0.37) | RAD52GAAFFAR1PPARGKDM4E | |
| SCHEMBL13638851 | 0.79 | ADORA2A (0.45) | RAD52GAAFFAR1PPARG | |
| Hydrochloric Acid SCHEMBL6096654 | 0.77 | FFAR1 (0.36) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| SCHEMBL6505168 | 0.77 | RAD52 (0.41) | RAD52GAAFFAR1NR1I2SMARCA2 | |
| SCHEMBL15148613 | 0.75 | RAD52 (0.45) | RAD52GAANR1I2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728500-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |