Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 3/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505168 | 0.87 | RAD52 (0.41) | ADORA2AADORA1GAARAD52FPR1 | |
| SCHEMBL13122882 | 0.82 | CRHR1 (0.40) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL12004750 | 0.81 | FPR1 (0.47) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL2448887 | 0.81 | FPR1 (0.47) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL2447116 | 0.81 | FPR1 (0.47) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL2938534 | 0.81 | FFAR1 (0.43) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL13162590 | 0.80 | SYK (0.46) | ADORA2AADORA1GAAFPR1FPR2 | |
| SCHEMBL2926286 | 0.80 | RAD52 (0.42) | GAARAD52FFAR1PPARG | |
| SCHEMBL12082229 | 0.80 | FFAR1 (0.56) | ADORA2AADORA1FPR1FPR2CRHR1 | |
| SCHEMBL12082307 | 0.80 | FFAR1 (0.56) | ADORA2AADORA1FPR1FPR2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |