Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638851 | 0.87 | ADORA2A (0.45) | RAD52GAAFFAR1PPARGADORA2A | |
| SCHEMBL5964474 | 0.81 | FFAR1 (0.40) | RAD52GAAFFAR1PPARGKDM4E | |
| SCHEMBL2926286 | 0.78 | RAD52 (0.42) | RAD52GAAFFAR1PPARGKDM4E | |
| SCHEMBL2928834 | 0.77 | RAD52 (0.41) | RAD52GAAFFAR1PPARGKDM4E | |
| Hydrochloric Acid SCHEMBL6496609 | 0.77 | RAD52 (0.41) | RAD52GAAFFAR1PPARGKDM4E | |
| Hydrochloric Acid SCHEMBL6497884 | 0.77 | RAD52 (0.39) | RAD52GAAFFAR1PPARGKDM4E | |
| SCHEMBL2928478 | 0.77 | RAD52 (0.39) | RAD52GAAFFAR1PPARGKDM4E | |
| SCHEMBL6223226 | 0.76 | GAA (0.43) | RAD52GAAFFAR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6504930 | 0.76 | RAD52 (0.40) | RAD52GAAFFAR1PPARGKDM4E | |
| Hydrochloric Acid SCHEMBL6505005 | 0.76 | RAD52 (0.38) | RAD52GAAFFAR1PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6923835-B2 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-08-02 | — | — | US | disclosed |